Testing statistical hypotheses of equivalence by Stefan Wellek

By Stefan Wellek

Equivalence checking out has grown considerably in significance during the last 20 years, specifically as its relevance to numerous purposes has turn into understood. but released paintings at the basic technique continues to be scattered in experts' journals, and for the main half, it specializes in the quite slender subject of bioequivalence assessment.

With a much broader viewpoint, checking out Statistical Hypotheses of Equivalence offers the 1st accomplished therapy of statistical equivalence checking out. the writer addresses a spectrum of particular, two-sided equivalence checking out difficulties, from the one-sample challenge with more often than not allotted observations of mounted recognized variance to difficulties concerning a number of samples and multivariate facts. The therapy contains a concise overview of easy mathematical effects on optimum assessments for equivalence, and the writer makes on hand on the net a set of desktop courses that let effortless implementation of the tools presented.

In a box as advanced and wealthy in capability functions as equivalence trying out, trying out Statistical Hypotheses of Equivalence stands by myself as a coherent reference that furnishes either the theoretical and sensible instruments wanted for facing equivalence trials of any complexity and in any section.

Show description

Read or Download Testing statistical hypotheses of equivalence PDF

Similar biostatistics books

Biostatistics: A Foundation for Analysis in the Health Sciences 6th Edition

Like its predecessors, this version stresses intuitive knowing of rules instead of studying by means of mathematical evidence. offers wide assurance of statistical systems utilized in the entire health and wellbeing technological know-how disciplines. This model incorporates a higher emphasis on laptop functions, and many of the statistical innovations contain the MINITAB instructions wherein they are often utilized.

Handbook of Modern Item Response Theory

Merchandise reaction thought has turn into an integral part within the toolkit of each researcher within the behavioral sciences. It offers a robust capability to review person responses to various stimuli, and the technique has been prolonged and constructed to hide many alternative types of interplay. This quantity offers a wide-ranging guide to merchandise reaction idea - and its purposes to academic and mental trying out.

Statistical Methods for the Analysis of Repeated Measurements

This e-book presents a finished precis of a large choice of statistical equipment for the research of repeated measurements. it truly is designed to be either an invaluable reference for practitioners and a textbook for a graduate-level path enthusiastic about tools for the research of repeated measurements. This booklet could be of curiosity to* Statisticians in teachers, undefined, and examine companies * Scientists who layout and research reviews during which repeated measurements are bought from each one experimental unit * Graduate scholars in facts and biostatistics.

Multivariate Survival Analysis and Competing Risks

Multivariate Survival research and Competing dangers introduces univariate survival research and extends it to the multivariate case. It covers competing dangers and counting procedures and offers many real-world examples, workouts, and R code. The textual content discusses survival info, survival distributions, frailty versions, parametric tools, multivariate information and distributions, copulas, non-stop failure, parametric probability inference, and non- and semi-parametric equipment.

Extra info for Testing statistical hypotheses of equivalence

Example text

Sensitivity and specificity should be used to refer to the intrinsic diagnostic performance of a given examination while predictive values enable us to evaluate the reliability of the results of the same examination once it is permormed. It should be borne in mind that these are not the same thing, as we will explain by demonstrating the influence of disease prevalence on predictive values. 5). ) to perform the examination, and on the radiologist’s skill in interpreting the examination. Sensitivity and specificity are not influenced by the disease prevalence in the study population (they are instead influenced by the degree, the stage of the disease, as we will demonstrate in the next section).

For instance, if we state that computed tomography (CT) is highly “specific” for the diagnosis of intracranial hemorrhage, we would mean that this imaging modality can reliably identify a hyperattenuation on nonenhanced scans as a hemorrhage. However, this statement has two different meanings: if really there is an intracranial hemorrhage, it is highly probable that CT can detect it; a CT diagnosis of intracranial hemorrhage is rarely a false positive. Using correct scientific terminology, these two sentences are the same as saying that CT has both high sensitivity and high positive predictive value for intracranial hemorrhage.

Throughout the book the reader will find several mathematical formulas. These have been included in their entirety for the readers willing to understand the mechanism of computing. However, a thorough understanding of the formulas is by no means required to grasp the general sense of the concepts and their practical use. Introduction 15 It is far from our intention to educate radiologists so that they can replace statisticians, as this appears neither possible nor useful. Instead it is our aim educate radiologists so that they may interact with statisticians with proficiency and critical judgment.

Download PDF sample

Rated 4.18 of 5 – based on 21 votes